small molecule kinase inhibitor library Search Results


small molecule kinase inhibitors lapatinib crizotinib erlotinib  (LC Laboratories)
90
LC Laboratories small molecule kinase inhibitors lapatinib crizotinib erlotinib
Small Molecule Kinase Inhibitors Lapatinib Crizotinib Erlotinib, supplied by LC Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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small molecule kinase inhibitors lapatinib crizotinib erlotinib - by Bioz Stars, 2026-10
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mek inhibitor pd-325901  (AbMole Bioscience)
90
AbMole Bioscience mek inhibitor pd-325901
Mek Inhibitor Pd 325901, supplied by AbMole Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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src tyrosine kinase small molecule inhibitors  (ARIAD Inc)
90
ARIAD Inc src tyrosine kinase small molecule inhibitors
Src Tyrosine Kinase Small Molecule Inhibitors, supplied by ARIAD Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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oral, small-molecule pan–cyclindependent kinase (cdk) inhibitor roniciclib (bay 1000394)  (Bayer AG)
90
Bayer AG oral, small-molecule pan–cyclindependent kinase (cdk) inhibitor roniciclib (bay 1000394)
Oral, Small Molecule Pan–Cyclindependent Kinase (Cdk) Inhibitor Roniciclib (Bay 1000394), supplied by Bayer AG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
oral, small-molecule pan–cyclindependent kinase (cdk) inhibitor roniciclib (bay 1000394) - by Bioz Stars, 2026-10
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4,000 small molecules from the biofocus kinase inhibitor library  (BioFocus DPI)
90
BioFocus DPI 4,000 small molecules from the biofocus kinase inhibitor library
4,000 Small Molecules From The Biofocus Kinase Inhibitor Library, supplied by BioFocus DPI, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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small molecule inhibitor of tyrosine kinase (sunitinib)  (Graybug Vision)
90
Graybug Vision small molecule inhibitor of tyrosine kinase (sunitinib)
Novel VEGF-Targeting Therapeutics in Clinical Development for Neovascular AMD or Diabetic Macular Edema Since September 2019
Small Molecule Inhibitor Of Tyrosine Kinase (Sunitinib), supplied by Graybug Vision, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
small molecule inhibitor of tyrosine kinase (sunitinib) - by Bioz Stars, 2026-10
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vegfr2/small-molecule tyrosine kinase inhibitor  (PanOptica)
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PanOptica vegfr2/small-molecule tyrosine kinase inhibitor
Approved or advanced in trials Wet AMD treatments.
Vegfr2/Small Molecule Tyrosine Kinase Inhibitor, supplied by PanOptica, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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small molecule kinase inhibitors biomol 2832a(v2.2)  (Biomol GmbH)
90
Biomol GmbH small molecule kinase inhibitors biomol 2832a(v2.2)
Approved or advanced in trials Wet AMD treatments.
Small Molecule Kinase Inhibitors Biomol 2832a(v2.2), supplied by Biomol GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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small molecule tyrosine kinase inhibitors iressa  (AstraZeneca ltd)
90
AstraZeneca ltd small molecule tyrosine kinase inhibitors iressa
Approved or advanced in trials Wet AMD treatments.
Small Molecule Tyrosine Kinase Inhibitors Iressa, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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small molecule igf-ir kinase inhibitor l000391906  (Piramal Phytocare)
90
Piramal Phytocare small molecule igf-ir kinase inhibitor l000391906
PANC-1 cells were pretreated with specific IGF-1R inhibitor <t>L000391906</t> (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. The cells were lysed in lysis buffer and then subjected to western blot analysis of indicated proteins ( b ) Blockage of IGF-1R signaling with L000391906 prevents BA145 mediated membrane translocation of p-Akt. Cells were treated L000391906 (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. Cells were stained with immunofluorescent p-Akt (Serine 473) antibody and analyzed by fluorescence microscopy ( c ) BA145 induces Akt activation in IGF dependent manner. PANC-1 cells were serum starved overnight and cotreated with either BA145 (40 μM) or wortmanin (1 μM) in presence or absence of IGF activator, insulin (100 ng/ml) for 3 h. Cells were lysed in lysis buffer for western blot analysis of Akt, S6K and their phosphorylated forms. β-actin was used as a loading control ( d ) Effect of L000391906 (4 μM) on the colony forming ability of BA145 (40 μM, 12 h) treated PANC-1 cells ( e ) Inhibition of IGFR-1 signaling enhanced BA145 mediated autophagy in PANC-1 cells. Cells were treated with BA145 (40 μM) and/or L000391906 (4 μM) for 6 h and then after stained with fluorescent antibody and analyzed by immunofluorescent microscopy. Columns, mean; bars, SD with ***p < 0.001 versus BA145.
Small Molecule Igf Ir Kinase Inhibitor L000391906, supplied by Piramal Phytocare, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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small molecule inhibitors of the anticancer target protein kinase b (also known as akt)  (AstraZeneca ltd)
90
AstraZeneca ltd small molecule inhibitors of the anticancer target protein kinase b (also known as akt)
PANC-1 cells were pretreated with specific IGF-1R inhibitor <t>L000391906</t> (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. The cells were lysed in lysis buffer and then subjected to western blot analysis of indicated proteins ( b ) Blockage of IGF-1R signaling with L000391906 prevents BA145 mediated membrane translocation of p-Akt. Cells were treated L000391906 (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. Cells were stained with immunofluorescent p-Akt (Serine 473) antibody and analyzed by fluorescence microscopy ( c ) BA145 induces Akt activation in IGF dependent manner. PANC-1 cells were serum starved overnight and cotreated with either BA145 (40 μM) or wortmanin (1 μM) in presence or absence of IGF activator, insulin (100 ng/ml) for 3 h. Cells were lysed in lysis buffer for western blot analysis of Akt, S6K and their phosphorylated forms. β-actin was used as a loading control ( d ) Effect of L000391906 (4 μM) on the colony forming ability of BA145 (40 μM, 12 h) treated PANC-1 cells ( e ) Inhibition of IGFR-1 signaling enhanced BA145 mediated autophagy in PANC-1 cells. Cells were treated with BA145 (40 μM) and/or L000391906 (4 μM) for 6 h and then after stained with fluorescent antibody and analyzed by immunofluorescent microscopy. Columns, mean; bars, SD with ***p < 0.001 versus BA145.
Small Molecule Inhibitors Of The Anticancer Target Protein Kinase B (Also Known As Akt), supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
small molecule inhibitors of the anticancer target protein kinase b (also known as akt) - by Bioz Stars, 2026-10
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small molecule inhibitor targeting serine/arginine-rich protein-specific kinase 1  (Exonate Ltd)
90
Exonate Ltd small molecule inhibitor targeting serine/arginine-rich protein-specific kinase 1
Novel VEGF-Targeting Therapeutics in Clinical Development for Neovascular AMD or Diabetic Macular Edema Since September 2019
Small Molecule Inhibitor Targeting Serine/Arginine Rich Protein Specific Kinase 1, supplied by Exonate Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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Image Search Results


Novel VEGF-Targeting Therapeutics in Clinical Development for Neovascular AMD or Diabetic Macular Edema Since September 2019

Journal: Investigative Ophthalmology & Visual Science

Article Title: The Landscape of Vascular Endothelial Growth Factor Inhibition in Retinal Diseases

doi: 10.1167/iovs.66.1.47

Figure Lengend Snippet: Novel VEGF-Targeting Therapeutics in Clinical Development for Neovascular AMD or Diabetic Macular Edema Since September 2019

Article Snippet: Tyrosine kinase , GB-102 , Graybug Vision , Small molecule inhibitor of tyrosine kinase (sunitinib) , Intravitreal , Phase II(ALTISSIMO/NCT03953079).

Techniques: Formulation

Approved or advanced in trials Wet AMD treatments.

Journal: Frontiers in Cell and Developmental Biology

Article Title: Age-Related Macular Degeneration Revisited: From Pathology and Cellular Stress to Potential Therapies

doi: 10.3389/fcell.2020.612812

Figure Lengend Snippet: Approved or advanced in trials Wet AMD treatments.

Article Snippet: PAN-90S06 , , Panoptica , VEGFR2/small-molecule tyrosine kinase inhibitor , No , Phase2/NCT03479372.

Techniques: Plasmid Preparation

PANC-1 cells were pretreated with specific IGF-1R inhibitor L000391906 (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. The cells were lysed in lysis buffer and then subjected to western blot analysis of indicated proteins ( b ) Blockage of IGF-1R signaling with L000391906 prevents BA145 mediated membrane translocation of p-Akt. Cells were treated L000391906 (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. Cells were stained with immunofluorescent p-Akt (Serine 473) antibody and analyzed by fluorescence microscopy ( c ) BA145 induces Akt activation in IGF dependent manner. PANC-1 cells were serum starved overnight and cotreated with either BA145 (40 μM) or wortmanin (1 μM) in presence or absence of IGF activator, insulin (100 ng/ml) for 3 h. Cells were lysed in lysis buffer for western blot analysis of Akt, S6K and their phosphorylated forms. β-actin was used as a loading control ( d ) Effect of L000391906 (4 μM) on the colony forming ability of BA145 (40 μM, 12 h) treated PANC-1 cells ( e ) Inhibition of IGFR-1 signaling enhanced BA145 mediated autophagy in PANC-1 cells. Cells were treated with BA145 (40 μM) and/or L000391906 (4 μM) for 6 h and then after stained with fluorescent antibody and analyzed by immunofluorescent microscopy. Columns, mean; bars, SD with ***p < 0.001 versus BA145.

Journal: Scientific Reports

Article Title: Interplay between cell cycle and autophagy induced by boswellic acid analog

doi: 10.1038/srep33146

Figure Lengend Snippet: PANC-1 cells were pretreated with specific IGF-1R inhibitor L000391906 (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. The cells were lysed in lysis buffer and then subjected to western blot analysis of indicated proteins ( b ) Blockage of IGF-1R signaling with L000391906 prevents BA145 mediated membrane translocation of p-Akt. Cells were treated L000391906 (4 μM) for 1 h and then cotreated with BA145 (40 μM) for 3 h. Cells were stained with immunofluorescent p-Akt (Serine 473) antibody and analyzed by fluorescence microscopy ( c ) BA145 induces Akt activation in IGF dependent manner. PANC-1 cells were serum starved overnight and cotreated with either BA145 (40 μM) or wortmanin (1 μM) in presence or absence of IGF activator, insulin (100 ng/ml) for 3 h. Cells were lysed in lysis buffer for western blot analysis of Akt, S6K and their phosphorylated forms. β-actin was used as a loading control ( d ) Effect of L000391906 (4 μM) on the colony forming ability of BA145 (40 μM, 12 h) treated PANC-1 cells ( e ) Inhibition of IGFR-1 signaling enhanced BA145 mediated autophagy in PANC-1 cells. Cells were treated with BA145 (40 μM) and/or L000391906 (4 μM) for 6 h and then after stained with fluorescent antibody and analyzed by immunofluorescent microscopy. Columns, mean; bars, SD with ***p < 0.001 versus BA145.

Article Snippet: To determine whether the induction of Akt expression by BA145 is dependent on IGF-IR, we employed small molecule IGF-IR kinase inhibitor, L000391906 having IC50 value of 0.006 μM (Piramal life sciences India).

Techniques: Lysis, Western Blot, Membrane, Translocation Assay, Staining, Fluorescence, Microscopy, Activation Assay, Control, Inhibition

Novel VEGF-Targeting Therapeutics in Clinical Development for Neovascular AMD or Diabetic Macular Edema Since September 2019

Journal: Investigative Ophthalmology & Visual Science

Article Title: The Landscape of Vascular Endothelial Growth Factor Inhibition in Retinal Diseases

doi: 10.1167/iovs.66.1.47

Figure Lengend Snippet: Novel VEGF-Targeting Therapeutics in Clinical Development for Neovascular AMD or Diabetic Macular Edema Since September 2019

Article Snippet: Serine/arginine-rich protein-specific kinase 1 , EXN407 , Exonate , Small molecule inhibitor targeting serine/arginine-rich protein-specific kinase 1 , Topical , Phases I and II(NCT04565756).

Techniques: Formulation